The COVID-19 pandemic has affected almost all aspects of life for a large proportion of the world’s population. The needs of the population living in low- and middle-income countries (LMIC) income countries such as Pakistan must be assessed and addressed to avoid widening existing global health inequalities. Pakistan was currently on an early but rising trajectory of the COVID-19 epidemic curve, and therefore assessing and monitoring the impact of COVID-19 is timely. In July 2019, this population based observational study was conducted to investigate the smoking behaviors in Pakistanthe STOP survey. The first wave of the survey recruited 6,027 participants. During consent gathering, survey participants were asked if they would be willing to take part in a future telephone follow-up in six-month’s time. This study also presented an opportunity to investigate the impact of the COVID-19 outbreak on this large nationally-representative population, in order to inform health, social care and policy responses